Instituto de Investigação e Inovação em Saúde, Universidade do Porto

Rua Alfredo Allen, 208 4200-135 Porto, Portugal
Phone: +351 226 074 900
Email: info@i3s.up.pt

Highlights

Joana Gaifem awarded with Maria de Sousa Prize for IBD Research

Joana Gaifem, a post-doctoral researcher in Pinho’s Lab, has recently been awarded with the Maria de Sousa prize. Currently in its 4th edition, this prize pays homage to the late Maria de Sousa, a pioneer in immunology and education in Portugal, and distinguishes notable young researchers in Portugal working in the health sciences.

New ICG article published in Gut on the impact of environmental pollutants in IBD

This study, published in the journal Gut, focuses on how environmental pollutants influence the risk of developing inflammatory bowel disease as well as disease outcomes. In total, information from a total of 32 human studies was utilized, allowing for a consolidation of the current knowledge on how escalating pollution levels relate to the increasing incidence of IBD globally.

New ICG article published in Carbohydrate Research on the role of glycans in trained immunity

Pinho’s lab has recently published a review article in the journal Carbohydrate Research. Trained immunity is an emerging concept in immunology and in this publication, first authored by Pedro Almeida, we highlight its tenets and delve into how glycans and their interactions with glycan-binding proteins (GBPs) influence key immunoregulatory networks in trained immunity.

New ICG article published in Nature Immunology identifies early IgG glycosylation alterations in Crohn’s Disease

Exciting news! In our most recent publication, we unveil a novel glycan signature in serum IgG antibodies years before the diagnosis of Crohn’s disease. In addition to predating Crohn’s disease and being associated with its complications, we show how this glycan signature elicits pro-inflammatory immune responses and contributes to disease susceptibility.

Inês Alves wins SPI Best Paper Award 2023!

Inês Alves, a researcher in Pinho's Lab, won the Best Paper Award 2023 from the Sociedade Portuguesa de Imunologia (SPI) for her paper titled "Host-derived mannose glycans trigger a pathogenic γδ T cell/IL-17a axis in autoimmunity" published in Science Translational Medicine.