Instituto de Investigação e Inovação em Saúde, Universidade do Porto
Rua Alfredo Allen, 208 4200-135 Porto, Portugal
Phone: +351 226 074 900
Email: info@i3s.up.pt
Immunology, Cancer & Glycomedicine
WHAT WE DO
Our Lab
Our group works at the interface of immunology, cancer and glycobiology, using a combination of in vitro, ex vivo and in vivo approaches.
Publications
The group’s research has been published in a number of high-impact publications over the years.
Research Topics
The group’s research explores several topics related to the impact of glycans on inflammation, autoimmunity and cancer.
OUR RESEARCH
OUR GROUP MAIN LINES OF RESEARCH:
Immune response
The exploitation of the cellular and molecular mechanisms by which glycans contribute to amplify immune response in chronic inflammation and autoimmunity.
OUR GROUP MAIN LINES OF RESEARCH:
Cancer glycosignatures
The investigation of how cancer-specific glycosignatures regulate the immunological networks in cancer.
HIGHLIGHTS
Pinho’s Lab publishes Science Immunology paper uncovering γδ T cell glycosylation as a therapeutic target in autoimmune diseases
Pinho’s Lab has recently published a groundbreaking study in the journal Science Immunology. Combining single-cell transcriptomics with experimental and functional approaches, the team demonstrated that IL-17A-producing γδT cells exhibit a distinctive glycosylation profile enriched in complex branched N-glycans. Importantly, once these glycans are depleted, γδ T cells are reprogrammed towards a highly pro-inflammatory phenotype.
Pinho's Lab Inês Alves Awarded L'Oréal Portugal Medal of Honor for Women in Science
Inês Alves, a junior researcher at Pinho’s Lab, has been awarded a L’Oréal Portugal Medal of Honor for Women in Science 2025, which recognizes young scientists with innovative projects in health and environmental research.
Pinho's Lab Beatriz Santos-Pereira Awarded SPI Travel Grant
Beatriz Santos-Pereira, a PhD student at Pinho’s Lab, has been awarded a Travel Grant from the Portuguese Society for Immunology (SPI) to attend the 1st Joint Annual Meeting of the French Society for Immunology (SFI) and the SPI, in Toulouse. She has also been selected for an oral presentation.