Instituto de Investigação e Inovação em Saúde, Universidade do Porto

Rua Alfredo Allen, 208 4200-135 Porto, Portugal
Phone: +351 226 074 900
Email: info@i3s.up.pt

Category research

publication, research

New ICG article published Portuguese Journal of Gastroenterology (GE) – Glycosylation profile as a potential biomarker for colorectal cancer progression

Exciting news! In a significant stride towards understanding colorectal cancer (CRC) progression, a recent study by our research group investigated the intricate role of glycosylation in serrated pathway lesions (SPLs), a specific pathway associated with colorectal cancer development. Published in…

Beatriz Pereira
February 9, 2024

Awards, research

Inês Alves, Among Top 5 Awardees of Maria de Sousa Prize for Lupus Research

Inês Alves, a postdoctoral researcher affiliated with Pinho’s Lab, has earned distinction as one of the top five recipients of the Maria de Sousa Award in the third edition of this prestigious competition. Presented by the Ordem dos Médicos and…

admin
November 30, 2023

publication, research

New ICG article published in Cellular & Molecular Immunology on immune regulatory networks coordinated by glycans and glycan-binding proteins in autoimmunity and infection

Exciting news! Our recent review paper published in Cellular & Molecular Immunology highlights the vital role of glycans in orchestrating immune responses.

admin
August 29, 2023

research, publication

New ICG article published in Trends in Immunology on glycome dynamics in T and B cell development

We have published an opinion article that highlights the pivotal role of glycosylation in immune system development and functionality.

admin
July 4, 2023

research, publication

New ICG article published in iScience on the muscle glycome in idiopathic inflammatory myopathies

Our recent study of idiopathic inflammatory myopathies (IIM), a group of chronic autoimmune diseases affecting muscles, has been published in iScience.

admin
June 22, 2023

research, publication

New ICG article published in Cellular & Molecular Immunology on the role of glycans in T-cell development and how it affects susceptibility to inflammatory diseases

Our researchers identified stage-specific glycome compositions during T-cell development and observed significant defects in key developmental checkpoints when restricting the N-glycosylation profile of thymocytes.

admin
June 21, 2023

Awards, research

ICG awarded a grant worth €280,000 by the Lupus Research Alliance

In a major achievement, Salomé Pinho's lab has been awarded a prestigious grant worth €280,000 by the Lupus Research Alliance.

admin
March 25, 2023

research, publication

New ICG article published in Science Translational Medicine on host-derived mannose glycans as triggers of γδ T cell/IL-17a axis in autoimmunity

Life-threatening autoimmune diseases, including systemic lupus erythematosus (SLE), lead to increasing disability over time, but the underlying mechanisms remain elusive. Now, a new study led by our group has shed light on the role of protein glycosylation in triggering autoreactive…

admin
March 15, 2023