Instituto de Investigação e Inovação em Saúde, Universidade do Porto
Rua Alfredo Allen, 208 4200-135 Porto, Portugal
Phone: +351 226 074 900
Email: info@i3s.up.pt

Our team at i3s had the pleasure of hosting a progress meeting for the GlycanSwitch ERC project from February 29th to March 1st. With a focus on understanding the role of IgG glycans in inflammatory diseases.

Exciting news! In a significant stride towards understanding colorectal cancer (CRC) progression, a recent study by our research group investigated the intricate role of glycosylation in serrated pathway lesions (SPLs), a specific pathway associated with colorectal cancer development. Published in…

Inês Alves, a postdoctoral researcher affiliated with Pinho’s Lab, has earned distinction as one of the top five recipients of the Maria de Sousa Award in the third edition of this prestigious competition. Presented by the Ordem dos Médicos and…

Exciting news! Our recent review paper published in Cellular & Molecular Immunology highlights the vital role of glycans in orchestrating immune responses.

We have published an opinion article that highlights the pivotal role of glycosylation in immune system development and functionality.

Our recent study of idiopathic inflammatory myopathies (IIM), a group of chronic autoimmune diseases affecting muscles, has been published in iScience.

Our researchers identified stage-specific glycome compositions during T-cell development and observed significant defects in key developmental checkpoints when restricting the N-glycosylation profile of thymocytes.

In a major achievement, Salomé Pinho's lab has been awarded a prestigious grant worth €280,000 by the Lupus Research Alliance.

Life-threatening autoimmune diseases, including systemic lupus erythematosus (SLE), lead to increasing disability over time, but the underlying mechanisms remain elusive. Now, a new study led by our group has shed light on the role of protein glycosylation in triggering autoreactive…