Category publication

This study, published in the journal Gut, focuses on how environmental pollutants influence the risk of developing inflammatory bowel disease as well as disease outcomes. In total, information from a total of 32 human studies was utilized, allowing for a consolidation of the current knowledge on how escalating pollution levels relate to the increasing incidence of IBD globally.

Pinho’s lab has recently published a review article in the journal Carbohydrate Research. Trained immunity is an emerging concept in immunology and in this publication, first authored by Pedro Almeida, we highlight its tenets and delve into how glycans and their interactions with glycan-binding proteins (GBPs) influence key immunoregulatory networks in trained immunity.

Exciting news! Our recent review paper published in Cellular & Molecular Immunology highlights the vital role of glycans in orchestrating immune responses.

We have published an opinion article that highlights the pivotal role of glycosylation in immune system development and functionality.

Our recent study of idiopathic inflammatory myopathies (IIM), a group of chronic autoimmune diseases affecting muscles, has been published in iScience.

Our researchers identified stage-specific glycome compositions during T-cell development and observed significant defects in key developmental checkpoints when restricting the N-glycosylation profile of thymocytes.

Life-threatening autoimmune diseases, including systemic lupus erythematosus (SLE), lead to increasing disability over time, but the underlying mechanisms remain elusive. Now, a new study led by our group has shed light on the role of protein glycosylation in triggering autoreactive…