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We have published an opinion article that highlights the pivotal role of glycosylation in immune system development and functionality.

Our recent study of idiopathic inflammatory myopathies (IIM), a group of chronic autoimmune diseases affecting muscles, has been published in iScience.

Our researchers identified stage-specific glycome compositions during T-cell development and observed significant defects in key developmental checkpoints when restricting the N-glycosylation profile of thymocytes.

Life-threatening autoimmune diseases, including systemic lupus erythematosus (SLE), lead to increasing disability over time, but the underlying mechanisms remain elusive. Now, a new study led by our group has shed light on the role of protein glycosylation in triggering autoreactive…