Joana Gaifem, a post-doctoral researcher in Pinho’s Lab, has recently been awarded with the Maria de Sousa prize. Currently in its 4th edition, this prize pays homage to the late Maria de Sousa, a pioneer in immunology and education in Portugal, and distinguishes notable young researchers in Portugal working in the health sciences.
This study, published in the journal Gut, focuses on how environmental pollutants influence the risk of developing inflammatory bowel disease as well as disease outcomes. In total, information from a total of 32 human studies was utilized, allowing for a consolidation of the current knowledge on how escalating pollution levels relate to the increasing incidence of IBD globally.
Pinho’s lab has recently published a review article in the journal Carbohydrate Research. Trained immunity is an emerging concept in immunology and in this publication, first authored by Pedro Almeida, we highlight its tenets and delve into how glycans and their interactions with glycan-binding proteins (GBPs) influence key immunoregulatory networks in trained immunity.
Exciting news! In our most recent publication, we unveil a novel glycan signature in serum IgG antibodies years before the diagnosis of Crohn’s disease. In addition to predating Crohn’s disease and being associated with its complications, we show how this glycan signature elicits pro-inflammatory immune responses and contributes to disease susceptibility.
Inês Alves, a researcher in Pinho's Lab, has been awarded a prestigious €10,000 Exploratory Research Grant by the European Society for Clinical Investigation (ESCI).
PhD student, Beatriz Santos-Pereira, has been awarded the EFIS-Immunology Letters Short-term Fellowship. Beginning in September 2024, she will undertake a three-month research internship at Leiden University Medical Center, supervised by Professors Manfred Wurher and Paul Hensbergen.
The 2nd GlycanTrigger General Assembly Meeting has concluded successfully in Leiden, The Netherlands. Hosted by Leiden University Medical Center (LUMC), the two-day event brought together researchers and collaborators from all partners across Europe and USA to discuss the latest developments in the project.
Inês Alves, a researcher in Pinho's Lab, won the Best Paper Award 2023 from the Sociedade Portuguesa de Imunologia (SPI) for her paper titled "Host-derived mannose glycans trigger a pathogenic γδ T cell/IL-17a axis in autoimmunity" published in Science Translational Medicine.
Pedro Almeida, a research technician in the group has been awarded an Immunology Letters Short-term Fellowship by the European Federation of Immunology Societies.
Our team at i3s had the pleasure of hosting a progress meeting for the GlycanSwitch ERC project from February 29th to March 1st. With a focus on understanding the role of IgG glycans in inflammatory diseases.
