Instituto de Investigação e Inovação em Saúde, Universidade do Porto
Rua Alfredo Allen, 208 4200-135 Porto, Portugal
Phone: +351 226 074 900
Email: info@i3s.up.pt

Exciting news! Our recent review paper published in Cellular & Molecular Immunology highlights the vital role of glycans in orchestrating immune responses.

We have published an opinion article that highlights the pivotal role of glycosylation in immune system development and functionality.

Our recent study of idiopathic inflammatory myopathies (IIM), a group of chronic autoimmune diseases affecting muscles, has been published in iScience.

Our researchers identified stage-specific glycome compositions during T-cell development and observed significant defects in key developmental checkpoints when restricting the N-glycosylation profile of thymocytes.

Life-threatening autoimmune diseases, including systemic lupus erythematosus (SLE), lead to increasing disability over time, but the underlying mechanisms remain elusive. Now, a new study led by our group has shed light on the role of protein glycosylation in triggering autoreactive…