Instituto de Investigação e Inovação em Saúde, Universidade do Porto
Rua Alfredo Allen, 208 4200-135 Porto, Portugal
Phone: +351 226 074 900
Email: info@i3s.up.pt
Exciting news! Our recent study of idiopathic inflammatory myopathies (IIM), a group of chronic autoimmune diseases affecting muscles, has been published in iScience. We found a crucial deficiency in the glycosylation pathway, which is linked to disease relapse and treatment resistance. Restoring the normal glycosylation profile led to decreased IL-6 levels, offering a potential target for new therapies. These results open up promising possibilities for personalized follow-up and improved treatments for IIM patients.