Instituto de Investigação e Inovação em Saúde, Universidade do Porto
Rua Alfredo Allen, 208 4200-135 Porto, Portugal
Phone: +351 226 074 900
Email: info@i3s.up.pt
Immunology, Cancer & Glycomedicine
WHAT WE DO
Our Lab
Our group works at the interface of immunology, cancer and glycobiology, using a combination of in vitro, ex vivo and in vivo approaches.
Publications
The group’s research has been published in a number of high-impact publications over the years.
Research Topics
The group’s research explores several topics related to the impact of glycans on inflammation, autoimmunity and cancer.
OUR RESEARCH
OUR GROUP MAIN LINES OF RESEARCH:
Immune response
The exploitation of the cellular and molecular mechanisms by which glycans contribute to amplify immune response in chronic inflammation and autoimmunity.
OUR GROUP MAIN LINES OF RESEARCH:
Cancer glycosignatures
The investigation of how cancer-specific glycosignatures regulate the immunological networks in cancer.
HIGHLIGHTS
Pinho Lab identifies new biomarker of colitis-associated cancer progression
Pinho’s Lab has recently published a landmark study on colitis-associated colorectal cancer (CAC) in the Journal of Crohn’s and Colitis! Therein, we demonstrate that a progressive increase in N-glycan branching at the T cell surface not only accompanies CAC development but also debilitates T cell function during carcinogenesis.
Pinho´s Lab receives Best Paper Award at the 2025 Annual Meeting of the Portuguese Society for Immunology
Pinho´s Lab was honoured to receive the Best Paper Award 2025 at the Annual Meeting of the Portuguese Society for Immunology (SPI – Sociedade Portuguesa de Imunologia), which took place in Lisbon last April.
Pinho’s Lab distinguished by the Mizutani Foundation for Glycoscience
Pinho’s Lab has recently been distinguished by the Mizutani Foundation for Glycoscience, receiving funding for a groundbreaking research project dedicated to harnessing glycans to improve immunotherapies for colorectal cancer (CRC).