Instituto de Investigação e Inovação em Saúde, Universidade do Porto
Rua Alfredo Allen, 208 4200-135 Porto, Portugal
Phone: +351 226 074 900
Email: info@i3s.up.pt
Immunology, Cancer & Glycomedicine
WHAT WE DO
Our Lab
Our group works at the interface of immunology, cancer and glycobiology, using a combination of in vitro, ex vivo and in vivo approaches.
Publications
The group’s research has been published in a number of high-impact publications over the years.
Research Topics
The group’s research explores several topics related to the impact of glycans on inflammation, autoimmunity and cancer.
OUR RESEARCH
OUR GROUP MAIN LINES OF RESEARCH:
Immune response
The exploitation of the cellular and molecular mechanisms by which glycans contribute to amplify immune response in chronic inflammation and autoimmunity.
OUR GROUP MAIN LINES OF RESEARCH:
Cancer glycosignatures
The investigation of how cancer-specific glycosignatures regulate the immunological networks in cancer.
HIGHLIGHTS
Joana Gaifem awarded with Maria de Sousa Prize for IBD Research
Joana Gaifem, a post-doctoral researcher in Pinho’s Lab, has recently been awarded with the Maria de Sousa prize. Currently in its 4th edition, this prize pays homage to the late Maria de Sousa, a pioneer in immunology and education in Portugal, and distinguishes notable young researchers in Portugal working in the health sciences.
New ICG article published in Gut on the impact of environmental pollutants in IBD
This study, published in the journal Gut, focuses on how environmental pollutants influence the risk of developing inflammatory bowel disease as well as disease outcomes. In total, information from a total of 32 human studies was utilized, allowing for a consolidation of the current knowledge on how escalating pollution levels relate to the increasing incidence…
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New ICG article published in Carbohydrate Research on the role of glycans in trained immunity
Pinho’s lab has recently published a review article in the journal Carbohydrate Research. Trained immunity is an emerging concept in immunology and in this publication, first authored by Pedro Almeida, we highlight its tenets and delve into how glycans and their interactions with glycan-binding proteins (GBPs) influence key immunoregulatory networks in trained immunity.